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SENSORY
EXPERIENCE

Social interactions generate lasting internal states.

NEURAL
CIRCUITS

Specific neurons encode, integrate and retrieve these experiences.

BEHAVIORAL OUTPUT

Internal states influence future social behavioral responses.

Our mission

Social interactions are among the strongest forces influencing future behaviors.

Winning or losing a fight, finding a mate, or competing for resources can permanently alter how animals behave. Yet we still know little about how these experiences are integrated and represented in the brain.

Our laboratory investigates the neural circuits that transform social experience into adaptive behavior.

Rather than studying aggression as a simple innate behavior, we view it as a dynamic behavioral state emerging from interactions between memory, sensory information and neuromodulation.

The main goal of our lab is thus to unravel the neurobiology of innate and social behaviors by identifying molecular mechanisms and their underlying neural circuitry, while in parallel exploring the impact of aggressive interactions on future social behaviors. To this end, we combine the powerful Drosophila melanogaster model system with sophisticated genetics, behavioral assays, machine-learning behavioral scoring, chemistry, immunohistochemistry, and functional imaging.

Our environement

We are part of the team EXPLAIN which aims to investigate the experience-dependent plasticity in insects, with a particular focus on cognitive functions. We belong to the Research center on Animal Cognition (CRCA) and the Center for Integrative Biology (CBI) in Toulouse, France.

CBI hosts more than 400 researchers from nearly 40 nationalities, providing a highly collaborative and interdisciplinary environment where neuroscience, behavior, genetics and cell biology converge. Internationally recognized for excellence in neuroethology and cognitive neuroscience, the CRCA offers outstanding opportunities for collaboration and access to state-of-the-art facilities for imaging, behavioral analysis, neurogenetics and imaging plateform, enabling research from molecules to neural circuits and behavior.

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WHY DROSOPHILA?

Despite having only 140,000 neurons, the fruit fly displays remarkably sophisticated social behaviors including aggression, courtship, learning and decision-making.

 

Its complete connectome and unparalleled genetic toolkit allow us to identify individual neurons, manipulate neural activity, and link brain function to behavior with extraordinary precision.

 

From single synapses to complex social interactions, Drosophila provides a unique model organism to investigate the fundamental principles of brain function.

 

Discover our approach →

MEET THE TEAM

 

Science is a collective adventure.

 

Our laboratory brings together researchers from diverse backgrounds who share a common curiosity about how brains generate behavior.

 

Meet the team →

PUBLICATIONS

 

30+Peer-reviewed publications

 

Our work spans neural circuits, learning and memory, aggression, social behavior, chemical communication and life-history evolution.

 

Browse publications →

LATEST NEWS

 

New publication:

A neuronal circuit mechanism gating aggressive escalation.

Science Advances 2026

 

Grant

Our ANR PRC BRaiN has been funded.

 

We are hiring a Research Engineer from our ANR grant

to perform functional imaging experiments.

 

All news →

Séverine Trannoy - Drosophila melanogaster -  Social behaviors - Aggression - Neural circuits - Internal state - Learning and memory

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